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Rb (phospho Ser249)Rabbit Polyclonal Antibody is designed to detect the retinoblastoma (Rb) protein phosphorylated at Serine 249 (Ser249). The Rb protein is a critical tumor suppressor that regulates cell cycle progression, particularly at the G1/S checkpoint, by controlling the activity of E2F transcription factors. Phosphorylation of Rb at specific residues, including Ser249, modulates its ability to bind E2F and governs cell proliferation.
Call No. | Packing | Price |
---|---|---|
OPR7000 | 20μL | 9188 |
OPR7000 | 60μL | 18060 |
OPR7000 | 120μL | 30429 |
OPR7000 | 200μL | 52479 |